Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 14 Researches
7.2
USERS' SCORE
Good
Based on 2 Reviews
8.7
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
15
Total Fat
1.5 g
2%**
Cholesterol
5 mg
2%
Total Omega 3 Polyunsaturates† providing: EPA (eicosapentaenoic acid) DHA (docosahexaenoic acid)
950 mg 504 mg378 mg
*** *** ***
Top Medical Research Studies
9
We delved into the potential of omega-3 polyunsaturated fatty acids, specifically docosahexaenoic acid (DHA), to combat glioblastoma, one of the most aggressive brain tumors.
In our study, we found that DHA treatment led to cell death in glioblastoma cells, as evidenced by signs of apoptosis and increased autophagy. Furthermore, tests in transgenic mice revealed a notable reduction in tumor size and increased activity reflected in cell death markers.
While these findings suggest a promising avenue for GBM treatment, further research is needed to fully understand how omega-3 fatty acids could be integrated into cancer therapies.
In our study, we found that DHA treatment led to cell death in glioblastoma cells, as evidenced by signs of apoptosis and increased autophagy. Furthermore, tests in transgenic mice revealed a notable reduction in tumor size and increased activity reflected in cell death markers.
While these findings suggest a promising avenue for GBM treatment, further research is needed to fully understand how omega-3 fatty acids could be integrated into cancer therapies.
Read More
8
We investigated the potential of docosahexaenoic acid (DHA) liposomes in treating glioblastoma, a challenging type of brain tumor. Using an advanced microfluidic system, we created liposomes that effectively penetrated GBM cells.
The results were promising; the DHA liposomes not only reduced tumor cell viability but also initiated cell death more effectively than regular DHA. This study opens new avenues for cancer treatment using omega-3 fatty acids in liposome formulations, highlighting their potential as a valuable therapeutic strategy.
The results were promising; the DHA liposomes not only reduced tumor cell viability but also initiated cell death more effectively than regular DHA. This study opens new avenues for cancer treatment using omega-3 fatty acids in liposome formulations, highlighting their potential as a valuable therapeutic strategy.
Read More
7
We analyzed data from nine observational studies to better understand the connection between fish consumption and brain tumor risk. Our findings suggest that increasing fish intake may be linked to a 17% lower risk of developing brain cancer, with a notable dose-response relationship.
However, we also emphasize the need for further research, including well-designed cohort studies, to confirm these initial results and clarify any potential confounding factors.
However, we also emphasize the need for further research, including well-designed cohort studies, to confirm these initial results and clarify any potential confounding factors.
Read More
Most Useful Reviews
9.5
Reduced depression symptoms
The most cost-effective content. Fish oil is needed for everything. If you have dry skin, depression, or high cholesterol, you will benefit from omega fats, which are essential for the brain and blood vessels. This packaging lasts over three months, and you only need to take one capsule daily instead of three or four. Quality is outstanding, and I felt the effects quickly. My depression showed improvement, irritability lessened, and my cholesterol normalised within two months. Solgar ensures their product is free from heavy metals. If my review was helpful, that would be lovely!
Read More
9.5
Increased mood & efficiency
I chose this fish oil for my child, and it's ideal! Omega-3 is crucial, especially for brain health and mood. The daily intake guidelines are 1g, with easy dosage at 950mg once a day, lasting 100 days for a reasonable price. My husband and I noticed increased efficiency and strength from the first days of taking it, along with improved mood. I ordered more immediately! If you find this review useful, thank you!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 14 Researches
7.2
- All Researches
9
We delved into the potential of omega-3 polyunsaturated fatty acids, specifically docosahexaenoic acid (DHA), to combat glioblastoma, one of the most aggressive brain tumors.
In our study, we found that DHA treatment led to cell death in glioblastoma cells, as evidenced by signs of apoptosis and increased autophagy. Furthermore, tests in transgenic mice revealed a notable reduction in tumor size and increased activity reflected in cell death markers.
While these findings suggest a promising avenue for GBM treatment, further research is needed to fully understand how omega-3 fatty acids could be integrated into cancer therapies.
In our study, we found that DHA treatment led to cell death in glioblastoma cells, as evidenced by signs of apoptosis and increased autophagy. Furthermore, tests in transgenic mice revealed a notable reduction in tumor size and increased activity reflected in cell death markers.
While these findings suggest a promising avenue for GBM treatment, further research is needed to fully understand how omega-3 fatty acids could be integrated into cancer therapies.
Read More
8
We investigated the potential of docosahexaenoic acid (DHA) liposomes in treating glioblastoma, a challenging type of brain tumor. Using an advanced microfluidic system, we created liposomes that effectively penetrated GBM cells.
The results were promising; the DHA liposomes not only reduced tumor cell viability but also initiated cell death more effectively than regular DHA. This study opens new avenues for cancer treatment using omega-3 fatty acids in liposome formulations, highlighting their potential as a valuable therapeutic strategy.
The results were promising; the DHA liposomes not only reduced tumor cell viability but also initiated cell death more effectively than regular DHA. This study opens new avenues for cancer treatment using omega-3 fatty acids in liposome formulations, highlighting their potential as a valuable therapeutic strategy.
Read More
8
We explored the potential of omega-3 fatty acid, docosahexaenoic acid (DHA), to combat glioblastoma, an aggressive brain tumor. By studying patient-derived GBM neural stem-like cells, we found that DHA treatment increases its levels in these cells, assisted by a protein called FABP7. This increase in DHA was linked to a reduction in the cells' ability to migrate, suggesting a possible therapeutic approach to limit tumor spread. However, more research is needed to fully understand the implications of DHA on glioblastoma treatment.
Read More
8
Omega-3 may aid olfactory recovery
We explored how omega-3 fish oil supplementation might support smell recovery in patients after endoscopic brain tumor surgery. In a multicenter trial involving 110 patients, those receiving omega-3 alongside nasal saline experienced less persistent loss of smell compared to peers without it.
Significantly, fewer patients in the omega-3 group reported olfactory issues at three and six months post-surgery. This suggests that omega-3 could play a protective role for the olfactory system during the recovery phase. However, surgery type also influenced outcomes.
Significantly, fewer patients in the omega-3 group reported olfactory issues at three and six months post-surgery. This suggests that omega-3 could play a protective role for the olfactory system during the recovery phase. However, surgery type also influenced outcomes.
Read More
8
Curcumin-DHA shows potential for glioblastoma
We explored a new formulation combining curcumin and docosahexaenoic acid (DHA) for treating brain tumors. By using microemulsions, this treatment showed impressive ability to penetrate the blood-brain barrier.
After administration, the curcumin concentrations in the brain were significantly higher—as much as 66 times greater compared to standard solutions. This suggests the potential of curcumin with DHA for effectively targeting glioblastoma brain cancer. Safety tests indicated that this approach does not harm surrounding tissues, highlighting its promising anticancer effects.
After administration, the curcumin concentrations in the brain were significantly higher—as much as 66 times greater compared to standard solutions. This suggests the potential of curcumin with DHA for effectively targeting glioblastoma brain cancer. Safety tests indicated that this approach does not harm surrounding tissues, highlighting its promising anticancer effects.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.7
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Reduced depression symptoms
The most cost-effective content. Fish oil is needed for everything. If you have dry skin, depression, or high cholesterol, you will benefit from omega fats, which are essential for the brain and blood vessels. This packaging lasts over three months, and you only need to take one capsule daily instead of three or four. Quality is outstanding, and I felt the effects quickly. My depression showed improvement, irritability lessened, and my cholesterol normalised within two months. Solgar ensures their product is free from heavy metals. If my review was helpful, that would be lovely!
Read More
9.5
Increased mood & efficiency
I chose this fish oil for my child, and it's ideal! Omega-3 is crucial, especially for brain health and mood. The daily intake guidelines are 1g, with easy dosage at 950mg once a day, lasting 100 days for a reasonable price. My husband and I noticed increased efficiency and strength from the first days of taking it, along with improved mood. I ordered more immediately! If you find this review useful, thank you!
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Mendanha D, Casanova MR, Gimondi S, Ferreira H, Neves NM. Microfluidic-Derived Docosahexaenoic Acid Liposomes for Targeting Glioblastoma and Its Inflammatory Microenvironment. ACS Appl Mater Interfaces. 2024;16:40543. doi:10.1021/acsami.4c01368
- Mendanha D, Gimondi S, Costa BM, Ferreira H, Neves NM. Microfluidic-derived docosahexaenoic acid liposomes for glioblastoma therapy. Nanomedicine. 2023;53:102704. doi:10.1016/j.nano.2023.102704
- Öcal Ö, Nazıroğlu M. Eicosapentaenoic acid enhanced apoptotic and oxidant effects of cisplatin via activation of TRPM2 channel in brain tumor cells. Chem Biol Interact. 2022;359:109914. doi:10.1016/j.cbi.2022.109914
- Choi WS, Xu X, Goruk S, Wang Y, Patel S, et al. FABP7 Facilitates Uptake of Docosahexaenoic Acid in Glioblastoma Neural Stem-like Cells. Nutrients. 2021;13. doi:10.3390/nu13082664
- Yan CH, Rathor A, Krook K, Ma Y, Rotella MR, et al. Effect of Omega-3 Supplementation in Patients With Smell Dysfunction Following Endoscopic Sellar and Parasellar Tumor Resection: A Multicenter Prospective Randomized Controlled Trial. Neurosurgery. 2020;87:E91. doi:10.1093/neuros/nyz559
- Kim S, Jing K, Shin S, Jeong S, Han SH, et al. ω3-polyunsaturated fatty acids induce cell death through apoptosis and autophagy in glioblastoma cells: In vitro and in vivo. Oncol Rep. 2018;39:239. doi:10.3892/or.2017.6101
- Shinde RL, Devarajan PV. Docosahexaenoic acid-mediated, targeted and sustained brain delivery of curcumin microemulsion. Drug Deliv. 2017;24:152. doi:10.1080/10717544.2016.1233593
- Lian W, Wang R, Xing B, Yao Y. Fish intake and the risk of brain tumor: a meta-analysis with systematic review. Nutr J. 2017;16:1. doi:10.1186/s12937-016-0223-4
- Harvey KA, Xu Z, Saaddatzadeh MR, Wang H, Pollok K, et al. Enhanced anticancer properties of lomustine in conjunction with docosahexaenoic acid in glioblastoma cell lines. J Neurosurg. 2015;122:547. doi:10.3171/2014.10.JNS14759
- Wang F, Bhat K, Doucette M, Zhou S, Gu Y, et al. Docosahexaenoic acid (DHA) sensitizes brain tumor cells to etoposide-induced apoptosis. Curr Mol Med. 2011;11:503.
- Cui PH, Petrovic N, Murray M. The ω-3 epoxide of eicosapentaenoic acid inhibits endothelial cell proliferation by p38 MAP kinase activation and cyclin D1/CDK4 down-regulation. Br J Pharmacol. 2011;162:1143. doi:10.1111/j.1476-5381.2010.01113.x
- Nasrollahzadeh J, Siassi F, Doosti M, Eshraghian MR, Shokri F, et al. The influence of feeding linoleic, gamma-linolenic and docosahexaenoic acid rich oils on rat brain tumor fatty acids composition and fatty acid binding protein 7 mRNA expression. Lipids Health Dis. 2008;7:45. doi:10.1186/1476-511X-7-45
- Denkins Y, Kempf D, Ferniz M, Nileshwar S, Marchetti D. Role of omega-3 polyunsaturated fatty acids on cyclooxygenase-2 metabolism in brain-metastatic melanoma. J Lipid Res. 2005;46:1278.
- Gramaglia A, Loi GF, Mongioj V, Baronzio GF. Increased survival in brain metastatic patients treated with stereotactic radiotherapy, omega three fatty acids and bioflavonoids. Anticancer Res. 1999;19:5583.
